InheriGen Pan-Ethnic Carrier Screening
What is InheriGen Pan-Ethnic Carrier Screening?
Carrier screening for hereditary genetic conditions is an important part of preconception and prenatal care. Historically, genetic carrier screening only covered single genes for specific ethnicities. According to the Census Bureau, by the year 2043 the majority of the US population will be so ethnically diverse that no single group will make up a majority. Thus, offering carrier screening based on a patient’s specific ethnicity is becoming increasingly more difficult. InheriGen carrier screening options perform carrier testing for multiple conditions at once, at a significantly lower cost than if each of these tests were run separately.
InheriGen Carrier Screening Panel Options
InheriGen Carrier Screening
The InheriGen Panel is comprised of over 180 hereditary diseases and more than 720 pathogenic variants tested from a single blood or oral rinse sample. These autosomal recessive and X-linked disorders are associated with childhood onset conditions, many of which are either lethal or have severe symptoms. It includes mutations chosen based on current ACMG and ACOG* recommendations as well as hundreds of variants selected through careful review of scientific literature and evaluation of clinical utility.
InheriGen Plus Carrier Screening
InheriGen Plus includes carrier screening for cystic fibrosis, spinal muscular atrophy, and fragile X syndrome in addition to the InheriGen panel.
Who Should be Offered InheriGen Pan-Ethnic Carrier Screening?
InheriGen is for Patients Who…
- Are of reproductive age
- Want the most information about their risks and options prior to and/or during pregnancy
- Belong to a high-risk ethnic group
- Are unsure of their ethnicity or biological background (adoption)
- Have a consanguineous partner
Why Choose InheriGen Carrier Screening?
Although there is no cure for many of the disorders included in these panels, knowing about one’s risk of having a child with a hereditary condition can be useful for patients who are pregnant or for couples planning a pregnancy. Family preparation options include:
- Medical treatment for disorders associated with symptoms that can be reduced
- Preimplantation genetic diagnosis (PGD)
- Prenatal diagnosis via chorionic villus sampling (CVS) or amniocentesis
- Option of egg/sperm donation
- Option of adoption
InheriGen is offered at an affordable price. For less than the price of one traditional genetic test, InheriGen provides a more comprehensive genetic screen.
Partner screening is available and recommended. Carrier screening is recommended for the reproductive partner of anyone determined to be a carrier for an autosomal recessive disorder. GenPath offers targeted variant analysis via InheriGen or full gene sequencing for all disorders on the panel with the exception of Gaucher disease, for which only mutation analysis is available.
To order InheriGen or partner screening, log in or open an account.