GenPath logo in conjunction with women's health

Sexual and Reproductive Health

Testing through GenPath Women’s Health improves the quality of care by using targeted detection in the diagnosis of STIs and other vaginal infections.

GenPath utilizes various multiple nucleic acid amplification tests (NAAT) which are able to identify multiple pathogens from a single collection. Our DNA and RNA amplification techniques provide high sensitivity and specificity compared to other methods.

One Collection, Targeted Detection

GenPath offers healthcare providers the choice of many collection devices in which to collect clinical samples. Thin Prep vial, SurePath vial, Aptima Swab collection, Roche tube, urine cup, Digene Swab and BD ProbeTec Urine Preservation Tube are all available options.

High Sensitivity, High Specificity

GenPath’s molecular testing options definitively identify pathogens to allow for more targeted treatment. The options are especially useful for detecting mixed infections and performance is not affected by collection variables like menses.

Convenience of Testing

The results of GenPath tests come from one laboratory in a concise, easy-to-read report.

Clinically Relevant Profiles

Testing profiles should be ordered based on patient history in conjunction with relevant clinical signs and symptoms.

Profiles

High Risk STI Profiles

For patients with new or multiple sex partners, in a high-risk demographic (under the age of 25), and/or who are having unprotected sex. Test for chlamydia and gonorrhea with the option of adding trichomonas and/or mycoplasma genitalium.

Cervicitis Profile

For patients with visible purulent or mucopurulent exudates from the cervical canal, endocervical bleeding, and/or ulcerative lesions on the ectocervix. Test for chlamydia, gonorrhea, trichomonas, mycoplasma genitalium, and herpes simplex virus types 1 and 2.

PID/Infertility/Pregnancy Loss Profile

For patients with symptoms of pelvic inflammatory diseases (PID) including lower abdominal pain, painful intercourse and urination and/or irregular menstrual bleeding. Patients may also have difficulty getting pregnant or experience multiple pregnancy losses. Tests for infections known to cause PID, including chlamydia, gonorrhea, trichomonas, mycoplasma, bacterial vaginosis organisms, aerobic vaginitis organisms, and ureaplasma.

Bacterial Vaginosis Profile

For symptomatic female patients with dysuria, pruritus, dyspareunia, vaginal discharge, or fishy vaginal odor. Discharge, when present, is usually milky white, but can be yellow or grey. Detects and quantifies lactobacillus species (non-pathogenic), gardnerella vaginalis, and atopobium vaginae. Detects megasphaera type 1 and bacterial vaginosis associated bacterium 2 (BVAB2). BV determination requires testing of all five organisms.

Aerobic Vaginitis (AV) Profile

For symptomatic female patients with dysuria, pruritis, dyspareunia, vaginal discharge, or foul vaginal odor. Detects and quantifies lactobacillus species (non-pathogenic) and detects Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Group A and B Streptococcus. AV determination requires testing of all five organisms.

Vulvovaginal Candidiasis Profile

For symptomatic females with dysuria, pruritus, dyspareunia and curd-like vaginal discharge. Tests for Candida genus and Candida albicans. If Candida genus is positive and Candida albicans is negative, the profile will reflex to five candida species (C. glabrata, C. dubliniensis, C. parapsilosis, C. tropicalis, and C. krusei).

Lesion Profiles

For patients presenting with papules, pustules, vesicles and/or ulcers on mucocutaneous tissue in the genital, anal, or oral areas. Profiles test for a combination of Herpes Simplex Virus (HSV) type 1 and type 2, Varicella Zoster Virus (VZV) Shingles and Treponema pallidum. Testing for LGV and CMV are also available as individual tests.

Disease/Infection/ConditionResponsible Organisms
ChlamydiaChlamydia trachomatis (CT)
GonorrheaNeisseria gonorrhea (GC) (NG)
TrichomoniasisTrichomonas vaginalis
Mycoplasma genitalium (M. gen)Mycoplasma genitalium
Bacterial vaginosis (BV)Anaerobic bacteria species including: Gardnerella vaginalis, Atopobium vaginae, Megasphaera type 1, Bacterial vaginosis-associated bacterium 2 (BVAB2), and Mobiluncus species (not part of panel but can be added)
Aerobic vaginitis (AV)Aerobic bacteria species including: Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Group A streptococcus, Group B streptococcus
Vulvovaginal candidasisCandida species (yeast): Candida genus, C. albicans C. glabrata, C. dubliniensis, C. parapsilosis, C. tropicalis, and C. krusei
Pelvic Inflammatory Disease (PID)CT, GC, mycoplasma genitalium, ureaplasma, anaerobic bacteria, aerobic bacteria, trichomonas vaginalis
SyphilisTreponema pallidum
HerpesHerpes simplex virus (HSV) type 1 and type 2