| Test Name |
EGFR Mutation Analysis |
| Also Known As |
EGFR BY PCR |
| Clinical Utility and/or Limitations |
A DNA sequencing test to identify patients with those specific mutations in the TK domain of the EGFR gene (exons 18-24). With this information, physicians will be able to select those patients who are most likely to respond to targeted lung
cancer therapy, including Iressa and Tarceva. Physicians can also use this information to predict drug resistance as identified by those patients who do not have those mutations. |
| Method |
Polymerase Chain Reaction and Sequencing |
| Reference Range |
See Report |
| |
| Ordering Details |
| Test Code |
5295-1 |
| Assay Schedule |
Setup 1 day a week, A.M |
| Turnaround Time |
3- 5 days |
| Preferred Specimen and Volume |
Formalin fixed paraffin embedded tissue. |
| |
| Specimen Handling Information |
| Specimen Storage |
Room temperature: Indefinite , Refrigerated: Indefinite |
| Specimen Transport |
Ship specimen ambient except during the months of May to September ship with ice pack to prevent damage from the heat. |
| Causes For Specimen Rejection |
Fresh Tissue. No Tumor in Block. No Patient Id and/or Surgical number on Specimen, Patient ID and/or Surgical number on specimen and Requisition doesn't match, Specimen without GenPath/BioReference requisition. |
| |
| Billing Information |
| CPT Codes |
83891
83892
83898x7
83904x7
83909x7
83912
|
| |
| Other Information |
