| Test Name |
PML/RARA, t(15;17) |
| Also Known As |
PML/RARA, t(15;17) |
| Panel? |
No |
| Clinical Utility and/or Limitations |
Diagnostic for AML-M3. Detected in about 5–8% of AML patients. Treatment withAcute Promyelocytic Leukemiaall-trans retinoic acid (ATRA) and other chemotherapy agents, can induce maturation.Usually associated with a favorable response to chemotherapy. |
| Diagnosis Under Consideration |
AML-M3 (APL) |
| Method |
FISH |
| |
| Ordering Details |
| Test Code |
5260-5 |
| Assay Schedule |
Mon - Sat, daily |
| Turnaround Time |
24-72hr Turnaround |
| Preferred Specimen and Volume |
2 mL Heparinized or EDTA Marrow, 5 mL Heparinized or EDTA Blood or Fresh Tissue in RPMI. |
| Alternate Specimen and Volume |
Non- decalcified Paraffin Embedded Tissue ( block) |
| |
| Specimen Handling Information |
| Specimen Storage |
Refrigerate fresh specimen until shipping, ship within 24 hrs. |
| Specimen Transport |
Ship specimen with ice pack. |
| Causes For Specimen Rejection |
No patient ID on Specimen, Patient ID on specimen and Requisition doesn't match, incorrect fixative (tube/solution), Specimen without GenPath/BioReference requisition. Frozen specimen. |
| |
| Billing Information |
| CPT Codes |
88368 (1) |
| |
