| Test Name |
MLL, t(11q23) |
| Also Known As |
MLL, t(11q23) |
| Panel? |
Yes |
| Clinical Utility and/or Limitations |
Detected in 50-80% of infant leukemia & 15% of adult ALL. Usually associated with a poor prognosis, regardless of age. *There are numerous variant translocations of 11q23, the more common of which
are associated with therapy-related AML, AML-M4 and M5, and have an
intermediate prognosis. |
| Diagnosis Under Consideration |
ALL, AML Diagnosis |
| Method |
FISH |
| |
| Ordering Details |
| Test Code |
5427-0 |
| Assay Schedule |
Mon - Sat, daily |
| Turnaround Time |
1-2 days |
| Preferred Specimen and Volume |
2 mL Heparinized or EDTA Marrow, 5 mL Heparinized or EDTA Blood or Fresh Tissue in RPMI. |
| Alternate Specimen and Volume |
Non- decalcified Paraffin Embedded Tissue ( block) |
| |
| Specimen Handling Information |
| Specimen Storage |
Refrigerate fresh specimen until shipping, ship within 24 hrs. |
| Specimen Transport |
Ship specimen with ice pack. |
| Causes For Specimen Rejection |
No patient ID on Specimen, Patient ID on specimen and Requisition doesn't match, incorrect fixative (tube/solution), Specimen without GenPath/BioReference requisition. Frozen specimen. |
| |
| Billing Information |
| CPT Codes |
88368 (1) |
| |
